Engineered Developmental Signals Could Illuminate Regenerative Medicine – UCSF News Services


Synthetic ‘Morphogens’ Can Guide Complex Tissue Development, Twin Studies Show
For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways. To create complex tissues and organs – from the pattern of rods and cones in the retina to the Byzantine filtration systems of the kidney – all these developing cells must constantly answer a fundamental but surprisingly difficult question: Where am I?
“In the field of regenerative medicine, we can use stem cells to make organoids to study disease, but we can’t yet put them into a person and
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